Among pazopanib-treated patients, Asians had higher incidences of several AEs compared with non-Asian patients, including any grade of PPE (50 vs 19%), AST increased (42 vs 19%), proteinuria (32 vs 10%), neutropenia/neutrophil count decreased (38 vs 5%), leukopenia/WBC count decreased (34 vs 4%), thrombocytopenia/platelet count decreased (33 vs 8%), ALT increased (44 vs 25%), bilirubin increased (19 vs 5%), and grade 3 hypertension (22 vs 11%). The gene discussed is GPT; the disease is hypertensive disorder.