Among pazopanib-treated patients, Asians had higher incidences of several AEs compared with non-Asians, including hypertension (54 vs 37%), PPE (48 vs 19%), ALT increased (42 vs 23%), AST increased (38 vs 18%), proteinuria (31 vs 8%), neutropenia/neutrophil count decreased (36 vs 5%), thrombocytopenia/platelet count decreased (31 vs 8%), anemia/hemoglobin decreased (17 vs 6%), and leukopenia/WBC count decreased (32 vs 4%). The gene discussed is GPT; the disease is anemia (phenotype).