Among Asian patients, the most common drug-related AEs (> 40% in either treatment arm) were hypertension, diarrhea, PPE, ALT increased, fatigue, neutropenia/neutrophil count decreased, thrombocytopenia/platelet count decreased, leukopenia/WBC count decreased, and anemia/hemoglobin decreased. The gene discussed is GPT; the disease is Decreased total neutrophil count.