CASP9 and cancer: In the present study, we showed that HHT could regulate the alternative splicing of Bcl-x and Caspase 9, resulting in a decrease in the levels of anti-apoptotic Bcl-xL and Caspase 9b mRNA with a concomitant increase in the mRNA levels of pro-apoptotic Bcl-xS and Caspase 9a in several cancer cells.