NPPB and hydrops fetalis: There were no differences from baseline values to the end of the 3-month treatment period in median BNP (11.4 [IQR 9.1–20.6] pg/mL to 10.6 [IQR 6.3–15.8] pg/dL, p = 0.061), mean EF (65.7 ± 5.0% to 65.3 ± 5.5%, p = 0.652), median BRS (9.6 [IQR 6.3-12.5] ms/mmHg to 7.9 [IQR 5.4–11.4] ms/mmHg, p = 0.592), and median LF/HF (1.3 [IQR 0.9–2.3] to 1.2 [IQR 0.7–2.0], p = 0.202) (Fig. 1, Table 2).