SERPINA1 and cystic fibrosis: Bronchiectasis is found in a variety of pulmonary diseases, both genetically caused and acquired, such as severe pulmonary infections and cystic fibrosis (CF), but is also a feature of Kartagener syndrome, chronic obstructive pulmonary diseases (COPD), alpha 1-antitrypsin deficiency, asthma, or primary immunodeficiencies [1–3].