Interestingly, data from online database TCGA indicated that Galectin-3 or TLR4 expression was not significantly correlated with the overall survival of patients with lung adenocarcinoma (sample size = 343, Additional file 1: Figure S1); considering that lower NEAT1 expression was significantly correlated with longer overall survival, the significance of NEAT1 being a potential prognosis marker might be greater. This evidence concerns the gene LGALS3 and lung adenocarcinoma.