In the patient based surveys (n = 14) these included: hypoglycaemia [49, 52, 55–57, 60, 66] glycaemic control [66], injecting in public [59], problems with injections [61, 69], insulin intensification [53], insulin adherence [48, 63], and perceptions of T2DM [62]. The gene discussed is INS; the disease is type 2 diabetes mellitus.