The quantitative data was produced by counting the 53BP1 and divided by the 2D projected area of all the nuclei imaged (n = 274 for saline; n = 310 for GNP-RGD; n = 307 for CIS; n = 357 for GNP-RGD; CIS). This evidence concerns the gene TP53BP1 and in situ carcinoma.