Due to the correlation between the levels of resistin and MCP-1, resistin and RBP4, visfatin and MCP-1, visfatin and SFRP5, as well as between the levels of MCP-1 and RBP4, the relative proportion of these studied adipokines may have a potential for the diagnosis of T2DM. The gene discussed is SFRP5; the disease is type 2 diabetes mellitus.