The levels of MCP-1 and SFRP5 were significantly decreased (P < 0.0001 and P = 0.003, respectively), while the levels of visfatin and RBP4 were significantly increased in patients with T2DM compared to those in control individuals (P = 0.005 and P = 0.021, respectively). The gene discussed is CCL2; the disease is type 2 diabetes mellitus.