PECAM1 and neoplasm: To prioritise potential therapeutic targets driving brain-specific metastasis, we identified 11 consensus genes contributing to enrichment in this 80-gene pathway across all brain-metastatic 4T1Br4 and GSE12276 tumours, two of which met the differential expression threshold [fold change (FC)≥1.5, P≤0.05] to qualify as members of the BrCa BSM gene set: FCER1G and PECAM1 (Table 2).