In this paper, the results of gene transcriptome sequencing, qTR-PCR, Western blotting, cytoimmunofluorescence and immunohistochemistry show that both SDF1 and CXCR4 are present in different tumor cells and even normal liver cells in vitro and in vivo before and after AnnexinA7 regulation. The gene discussed is CXCR4; the disease is neoplasm.