The expression changes of VEGFC/D-VEGFR3/NRP2 and SDF1/CXCR4 are almost completely identical between tumor cells and normal cells, between high and low lymph node metastatic potential of liver cancer cells as well as between downregulation and upregulation of AnnexinA7 (unpublished data). The gene discussed is CXCR4; the disease is liver cancer.