In experimental studies, treatment with angiopoietin-1 reduced tubular injury in unilateral ureteral obstruction [15], decreased albuminuria in streptozotocin-induced type-1 diabetes [16], and stabilized peritubular capillaries in folic acid nephropathy, though this was accompanied by profibrotic and inflammatory effects [17]. Here, ANGPT1 is linked to Ureteral obstruction.