SQSTM1 and Miyoshi myopathy: The silencing of autophagy essential genes, such as Atrogin 7 (Atg7) or Sequestosome-1/p62 (SQSTM1/p62), affects MM cell survival and, in particular, silencing of SQSTM1/p62, together with bortezomib treatment, enhanced bortezomib-dependent toxicity and ubiquitinated protein accumulation [52].