Interestingly, in order to clarify the molecular mechanisms by which RP5-1024C24.1 is able to affect cell growth and migration in thyroid carcinoma cells, we found that the restoration of RP5-1024C24.1 is able to increase PTEN protein levels and to reduce Akt-Ser473 phosphorylation, thus suggesting that the modulation of this pathway could account for the effects of RP5-1024C24.1 on cell proliferation and migration [30,31,32,33,34]. The gene discussed is AKT1; the disease is thyroid gland carcinoma.