MPPED2 and thyroid cancer, nonmedullary, 2: Statistical analyses of MPPED2 expression in thyroid carcinoma samples compared to their adjacent normal tissue reveal significant differences between tumours and their corresponding normal tissue in the following categories: whole cohort (p < 0.001), PTC (p < 0.001), FTC (p < 0.001), PDC (p < 0.001), ATC (p = 0.003) (Table 2).