Migration was not altered in IKKα- or NF-ĸB2-depleted NSCLC cells upon overexpression of DARPP-32, but migration was substantially increased when DARPP-32 was overexpressed in the absence of IKKα or NF-ĸB2 knockdown (Fig. 5c, d). The gene discussed is PPP1R1B; the disease is non-small cell lung carcinoma.