BRCA2 and breast cancer: Among BC cases the lowest mean PBL-TL value was detected in VUS BRCA2 variants (10 subjects) (Mean (S.E.): 1.78 (0.19)) no significant variation in mean PBL-TL was seen in patients tested positive for the presence of BRCA pathogenic mutations (mean (SE) = 1.94 (0.17), p = 0.397) (Table 3)