CD34 and chronic myelogenous leukemia, BCR-ABL1 positive: By the generation of CML-iPSCs, the authors discovered olfactomedin 4 as a novel factor that contributes to the survival and growth of somatic lin(-)CD34(+) cells from the bone marrow of patients with CML in the chronic phase, but not primitive hematopoietic cells from normal bone marrow [14].