It has been reported that the protein level of YAP, one of the downstream transcriptional coactivators of Hippo signaling pathway, was tightly correlated with mTOR activity in several types of tumor cells, including pulmonary lymphangioleiomyomatosis, hepatic angiomyolipomas, and renal angiomyolipomas [28]. This evidence concerns the gene MTOR and hepatic angiomyolipoma.