AKT1 and breast carcinoma: Bacillus subtilis lipopeptides have been found to have anti-tumor effects (Zhao et al. 2017), including inhibitory effects on human breast cancer in vitro and in vivo through the disruption of the Akt pathway (Dey et al. 2015), and the induction of apoptosis of melanoma A 375 cells by specific interaction with the plasma membrane (Janek et al. 2013) and human leukemia K562 cells associated with caspase-3 and poly(ADP-ribose)polymerase (PARP) protein (Wang et al. 2007).