CXCL8 and parasitic infectious disease: For instance in response to parasitic infection, Dendritic Cells (DCs), PMNs specially neutrophils, and macrophage produce different cytokines and chemokines such as IL12, IL8, IL1, IL6, TNFα and INFγ which contribute to the development of the inflammatory response by the direct activation of multiple apoptotic pathways [20, 21].