In this study, the effect of VKORC1 rs9923231, CYP4F2 rs2108622 and NQO1 rs1800566 genotypes on the daily stable warfarin dose in Sichuan Han Chinese patients with catheter ablation of atrial fibrillation was determined, and the allelic frequency and genetic distribution of these genotypes were also compared with other ethnic populations. Here, VKORC1 is linked to atrial fibrillation.