Patients’ characteristics in the EF+ group vs. those in the EF− group were as follows: median age (range), 62 (41–74) vs. 65 (47–80) years; ECOG PS 0/1, 19/9 vs. 58/30 patients; median tumor size (range), 80 (12–110) vs. 70 (20–200) mm; total circumferential lesion, 20 vs. 40 patients; esophageal stenosis, 18 vs. 56 patients; aortic invasion, 16 vs. 38 patients; tracheal or bronchial invasion, 24 vs. 68 patients; and CRP ≥1.00 mg/dL, 19 vs. 29 patients, respectively (Table 1). This evidence concerns the gene CRP and neoplasm.