Other proteins within our differentially expressed proteins lists, which may be involved with cytoskeletal assembly/integrity include Pdlim5 [46] (upregulated in gastrocnemius) and Ldb3 (also called ZASP, upregulated in soleus), which interacts with α-actinin and mutations of which are associated with myopathy [47]. The gene discussed is PDLIM5; the disease is myopathy.