Well-differentiated HCCs were mostly HPC marker negative (p = 0.011), whereas HCCs with vascular invasion were mostly HPC marker-positive (NCAM: p = 0.003, CK19: p = 0.007) (Table 2), suggesting that tumour expression of HPC markers was related to the malignant potential of HCC. The gene discussed is NCAM1; the disease is neoplasm.