AFP and neoplasm: For overall survival (OS), two HPC markers, CK19 and EpCAM, and nine clinicopathological characteristics (AFP ≥60 mg/dl, AFP-L3 ≥20%, DCP ≥300 mAU/ml, age ≥60, C-P score B or C, vascular invasion, TNM stages II or III, and tumour size ≥5 cm and histological grade mod or mod/poor or poor) were revealed as prognostic factors by univariate analysis.