TEK and mesothelioma: In agreement with previous observations [17, 18], the anti-mesothelioma properties of Murine Tek-deltaFc should be mainly ascribed to its anti-angiogenic potential: First, in contrast to a previous study, demonstrating that Ang-1 promotes proliferation of Tie-2 (+) mesothelioma cells [15], we found that neither angiopoietins nor the inhibitor impacted the in vitro growth of the cells in our study, even though they both express active Tie-2.