CORIN and congestive heart failure: However, in rats with decompensated CHF, corin mRNA levels were increased compared to compensated CHF (1.40 ± 0.19 vs. 0.81 ± 0.06, respectively; P < 0.01) and sham-operated rats (1.40 ± 0.19 vs. 1.00 ± 0.006, respectively; P < 0.05).