CORIN and congestive heart failure: Specifically, western blot analysis of the immunoreactive peptide revealed a significant increase in corin abundance in the pulmonary tissue of the decompensated CHF, as compared to compensated CHF (7.37 ± 3.03 vs. 0.76 ± 0.14, respectively; P < 0.01) and sham-operated rats (7.37 ± 3.03 vs. 1.00 ± 0.1680, respectively; P < 0.01), (Figure 5D and 5E).