Interestingly, higher levels of interferon (IFN) gamma-induced protein 10 (IP-10) were associated with exanthema, whereas lower levels of granulocyte-colony stimulating factor (G-CSF) were detected in subjects with fever, suggesting that cytokines can either induce or control the clinical symptoms of ZIKV infection. This evidence concerns the gene CXCL10 and Zika virus infectious disease.