The expression of NONO and ERG was detected in 61/81 (75.3%) and 53/81 (65.4%) gastric cancer tissues, and higher in cases with local invasion (P < 0.001 and P < 0.001), lymph node metastasis (P < 0.001 and P < 0.001), distant metastasis (P = 0.004 and P < 0.001), or advanced tumor-node-metastasis (TNM) stage (P < 0.001 and P < 0.001, Supplementary Table S1). The gene discussed is ERG; the disease is gastric cancer.