TRPC1 and osteosarcoma: There are numerous studies showing a clear correlation between cancer patient survival and TRP channel expression, e.g., TRPC1, TRPM2 and TRPV4 in breast cancer [25,26,27], TRPM7 in PDAC [28], TRPM8 in bladder cancer and osteosarcoma [29,30] and TRPV2 in breast and esophageal cancer [31,32] to name just a few examples (see also Table 2).