According to our recent observations [20], exogenous B-Myb overexpression in NSCLC promoted G1–S phase transition progression; caused transactivation of multiple downstream genes such as CCNA1, COL11A1, COL6A1, MMP2, NID1, and FLT4; and activated ERK and Akt signaling pathways. This evidence concerns the gene COL11A1 and non-small cell lung carcinoma.