The non-hyperdiploid MM is associated with chromosomal translocations involving the immunoglobulin heavy-chain (IgH) locus and the loci encoding MMSET, FGFR3, CCND3 (cyclin D3), CCND1 (cyclin D1), MAF (c-Maf) or MAFB [15,16,17,18,19,20]. The gene discussed is CCND3; the disease is Miyoshi myopathy.