The aims of this study were 1) to investigate PRCP activity in different primary cell types (monocytes, macrophages, lymphocytes, granulocytes, endothelial cells) to determine the distribution of PRCP activity in the circulation and 2) to measure PRCP activity in serum collected from individuals categorized based on their BMI and the diagnosis of metabolic syndrome (MS). The gene discussed is PRCP; the disease is myeloid sarcoma.