The C-indices for the models including all three biomarkers (GDF-15, CRP and Cystatin C) to predict HF (0.824; 95% CI: 0.793, 0.855, p = 0.018) and death from CHD (0.839; 95% 0.808, 0.870, p = 0.011) were significant. This evidence concerns the gene CST3 and coronary artery disorder.