ATP2A3 encodes a sarcoplasmic/endoplasmic reticulum Ca2+ ATPase and disorders of Purkinje cell (LeDoux, 2011) and dopaminergic (Surmeier, Halliday, & Simuni, 2017) calcium homeostasis have been linked to dystonia and Parkinson disease, respectively. This evidence concerns the gene ATP2A3 and Parkinson disease.