Although dystonia is not a clinical feature typically reported in SPG31 and SPG72 cases, dystonia is not uncommon in several other SPGs, including SPG7, SPG15, SPG26, SPG35, and SPG47 (van Gassen et al., 2012; Klebe, Stevanin, & Depienne, 2015). The gene discussed is REEP2; the disease is Dystonia.