MiR‐17‐92 displays different expression level during B‐cell development: they are enhanced level in progenitor cells, and their expression decreases highly when pre‐B becomes immature B cells.6 MiR‐17‐92 expression is up‐regulated in CD4+ T cells from lupus patients and multiple sclerosis.7, 8 Decreased expression of miR‐17‐92 has been found during differentiation towards CD8+ T cells.9 It is generally recognized that these immune‐related cells were related to the development of SLE. Here, CD8A is linked to systemic lupus erythematosus.