Studies have additionally documented the potential of dental mesenchymal stem cells derived from deciduous teeth or periodontal tissues to differentiate into insulin producing cells as a non-invasive source of cells for islet generation that can be used for autologous transplantation for the treatment of children with type I diabetes without risk of rejection and calls for banking deciduous teeth for clinical application (Govindasamy et al., 2011; Lee et al., 2014). Here, INS is linked to type 1 diabetes mellitus.