Among the selected asthma-related PAHs metabolites (2-OHFLU, 4-OHPHE, 1-OHPHE, 2-OHPHE, 1- OHPYR and ∑OH-PAHs), we did not find any metabolites were significantly associated with the expressions of IL-9 and eotaxin, after adjusted for gender, age, occupational dust exposure, tobacco smoking, BMI. The gene discussed is IL9; the disease is asthma.