Additionally, since it has been reported that glutamate transporter expression in astrocytes inversely correlates with the expression of glial fibrillary acidic protein GFAP39, which is known to be strongly increased in brain parenchyma surrounding glioma12, we investigated whether Kv1.3 blockade affected GFAP expression in our glioma mouse model. This evidence concerns the gene KCNA3 and glioma.