RXRA and cancer: We found that the cancer-related TFs, MYC (Supplementary Fig. 6c), and ELF1 (Supplementary Fig. 6d) indeed had binding sites enriched (one-sided Fisher’s exact Q-value < 1e-10) in peaks with sensitive width in human cancer cells, while the liver-specific TFs, HNF4a (Supplementary Fig. 6e), and RXRa (Supplementary Fig. 6f–h) were also enriched (one-sided Fisher’s exact Q-value < 1e-10) in peaks with robust width in mouse liver.