CLK2 and colorectal cancer: To investigate how high CLK2 kinase expressions affected sensitivity to T‐025, we asserted the AS event caused by T‐025 in additional solid cancer cell lines with different CLK2 expression and sensitivity, such as NCI‐H1048 lung cancer cells (IC50 at 84.4 nmol/l), COLO320HSR colorectal cancer cells with high CLK2 expressions (IC50 at 91.8 nmol/l), and 786‐O kidney cancer cells with low CLK2 expressions (IC50 at 340 nmol/l).