DYRK1A and breast cancer: In addition, we found that the RNAi‐mediated downregulation of MYC reduced the growth suppressive effect of T‐025 in MYC‐amplified SK‐BR3 or MCF7 breast cancer cell lines, whereas the depletion of DYRK1A did not reduce the effect of T‐025 (Fig 5I and Appendix Fig S4B).