Abdul-Ghani et al. have reported that individuals whose plasma glucose concentrations return to equal to or below the fasting levels by 30 min after a glucose load showed the highest insulin sensitivity, the highest insulin secretion, and the lowest risk for future diabetes, compared with those who required >30 min for their plasma glucose to return to fasting levels in Mexican Americans [15] and Caucasians [21]. This evidence concerns the gene INS and diabetes mellitus.