Overexpression of Uc160 or Uc346 in CRC cell lines resulted to an increase in the proliferation as well as in the migration rate of the cells, supporting an oncogenic role for these long non-coding RNAs in the metastatic process of CRC, as it has been reported for other T-UCRs [53]. This evidence concerns the gene RFX4-AS1 and colorectal carcinoma.