Furthermore, deregulated expression of a large number of genes associated with other hematopoietic tumors as well as other cancers have been identified in PTCL, including SNF5 [16], LIN28B [17], MYC [18, 19], PI3K [18], mTOR [18], AKT [19, 20], MAF [21], genes involved in Notch signaling [22], members of the Polycomb repressive complex 2 including BMI1 [23] as well as genes regulating intrinsic [24] and extrinsic apoptosis [25]. The gene discussed is AKT1; the disease is mature T-cell and NK-cell non-Hodgkin lymphoma.