Both compounds (JWH-133 and RTX) induced a significant increase of Caspase-3 expression in T-ALL patients and Jurkat cells (Figure 1A, 1B) at mRNA level, where we evaluated the Caspase 3 mRNA and also by Western Blot where the Pro-Caspase 3 levels were examined (Figure 1C, 1D). Here, CASP3 is linked to acute lymphoblastic leukemia.