ABCB1 and cancer: It has been shown that in the subpopulation of cancer stem cells NF-κB significantly increases the expression of genes of cellular proteins associated with chemoresistance and invassiveness of cancers, among which intensifies the expression and function of P-glycoprotein, reduces cell susceptibility to apoptosis, enhances repair of DNA damage in cancer cells and increases the ability of new migration and metastasis [65, 66, 68, 69].