In the two cohorts (NSCLC and mCRC), we observed a correlation between Qubit quantification of cfDNA quantity and the number of WT haploid GE for KRAS among samples obtained from mCRC patients (R2 = 0.91) and NSCLC patients (R2 = 0.86) (Supplementary Figure 1). Here, KRAS is linked to non-small cell lung carcinoma.