Recently, the extensive antitumor effects of resveratrol have been revealed, and its functions include inhibiting proliferation, inducing apoptosis, repressing invasion and migration, and impairing the tumor-initiating stem-like properties via several signaling pathways, such as the sonic hedgehog pathway and the PI-3K/Akt/NF-kappaB pathway [45, 46]. This evidence concerns the gene AKT1 and neoplasm.