PPARGC1A and metabolic syndrome: Improvements of dyslipidemia by argan oil are consistent with studies on the expression of nuclear genes controlling lipid metabolism which, as highlighted in the next section, have shown in an animal model of human sepsis that argan oil upregulates hepatic expression of PGC-1α, leading to parallel coactivations of the nuclear receptors—PPARα, ERRα, and HNF-4α—which govern FAOx metabolism and gluconeogenesis [6].