ACOX1 and diabetes mellitus: Consistent also with the relevance of the emerging model of aging appearing on Figure 3 are as developed thereafter (i) the remarkable anti-inflammatory potential of ACOX1 through generation of precursors of lipid mediators with potent anti-inflammatory activity (specialized proresolving mediators, SPM), (ii) protection given by either argan oil use or ACOX1 induction in signaling pathways improving diabetes and metabolic syndromes and (iii) protection given by SPM in age-related disorders.