FACS-sorted CD3− CD14− CD123− CD193− neutrophils (Figure 1B) were co-cultured with bone marrow-derived BMSCs (Figure 1A) and induced a 38% decrease in mineralized ECM after 4 weeks of culture in OM analyzed by Alizarin Red staining (p < 0.05, n = 4, Figures 2D,E). The gene discussed is CCR3; the disease is ocular melanoma.