PGLYRP1 and infection: Moreover, summer adult honeybees upregulate seven types of immune proteins, namely, defensin1, abaecin, hymenoptaecin, phenoloxidase (PO), carboxylesterases (CEs), peptidoglycan recognition proteins (PGRPs), and immune responsive protein 30 (IRP30), after infection with E. coli, while only hymenoptaecin, defensin1 and IRP30 are induced in winter honeybees.