LGALS9 and cancer: Moreover, seven research groups reported that Gal-9 indicated a trend toward a poor clinical outcome or had no correlation with the prognosis of various cancers (Jiang et al., 2013; Kong et al., 2014; Schulkens et al., 2014; Grosset et al., 2016; Ohue et al., 2016; Choi et al., 2017; Melief et al., 2017).